Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.68 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.68 |
| ▸ | PI4KA | P42356 | 15/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 15/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.56 |
| ▸ | PIP5K1C | O60331 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249741 | 0.81 | FTO (1.00) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL8773471 | 0.79 | PIK3CA (1.00) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL7285684 | 0.78 | RAB9A (1.00) | PI4KAPI4KBPIK3CANPC1TP53 | |
| SCHEMBL24156360 | 0.77 | MEN1 (0.52) | FTOALKBH5NPC1HTTRAB9A | |
| SCHEMBL29646253 | 0.77 | PIK3CA (0.82) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL5532470 | 0.77 | PIK3CA (0.82) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL24156346 | 0.74 | TDP1 (0.52) | FTOALKBH5NPC1HTTRAB9A | |
| SCHEMBL25303323 | 0.74 | PI4KA (0.72) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL1847514 | 0.74 | PIK3CA (0.70) | FTOALKBH5PI4KAPI4KBPIK3CA | |
| SCHEMBL24156361 | 0.74 | MEN1 (0.58) | NPC1MAPTHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304558-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-10-02 | — | — | US | disclosed |
| US-12391674-B2 | Heterocyclic compounds for the treatment of epilepsy | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-08-19 | — | — | US | disclosed |
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
| EP-3887358-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | Otsuka Pharmaceutical Co., Ltd. (JP) | 2021-10-06 | — | — | EP | disclosed |
| CN-113166076-A | Heterocyclic compounds for the treatment of epilepsy | 大塚制药株式会社 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020111263-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391674-B2 | Heterocyclic compounds for the treatment of epilepsy | SLC6A11, SCN1A, SCN1B | FTO 2412/4885ALKBH5 2849/4885PI4KA 4411/4885 |
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | FTO 2412/4885ALKBH5 2849/4885PI4KA 4411/4885 |
| US-20250304558-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, KCNH1 | FTO 2814/4885ALKBH5 3361/4885PI4KA 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.