Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156660 | 0.71 | TP53 (0.38) | DRD2DRD4MEN1KMT2ACYP1A2 | |
| SCHEMBL24156623 | 0.69 | DRD2 (0.31) | DRD2DRD4HIF1A | |
| SCHEMBL14660900 | 0.67 | CYP2C19 (0.42) | PDE3BPDE3A | |
| SCHEMBL29202265 | 0.67 | MEN1 (0.45) | MEN1KMT2ACYP1A2CYP2C9NR3C2 | |
| SCHEMBL25897315 | 0.67 | ADRA2A (0.36) | DRD2DRD4MEN1KMT2ACYP1A2 | |
| SCHEMBL25897326 | 0.67 | HIF1A (0.36) | DRD2DRD4MEN1KMT2ACYP1A2 | |
| SCHEMBL9537880 | 0.67 | MAPT (0.51) | MEN1KMT2ACYP1A2CYP2C9NR3C2 | |
| SCHEMBL29766649 | 0.67 | ADRA2A (0.36) | DRD2DRD4MEN1KMT2ACYP1A2 | |
| SCHEMBL26967792 | 0.64 | MEN1 (0.41) | MEN1KMT2ACYP1A2CYP2C9MAPK1 | |
| SCHEMBL14661495 | 0.62 | HTT (0.32) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259208-A1 | TYK-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-12-30 | — | — | WO | disclosed |