Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 10/20 | 0.65 |
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.65 |
| ▸ | AR | P10275 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4392302 | 0.95 | RAB9A (0.59) | RAB9ANPC1CYP3A4CYP1A2AR | |
| Bromide SCHEMBL4383708 | 0.95 | RAB9A (0.59) | RAB9ANPC1CYP3A4CYP1A2AR | |
| Hydrochloric Acid SCHEMBL10653147 | 0.95 | RAB9A (0.65) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL170196 | 0.95 | RAB9A (0.64) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL29374931 | 0.95 | RAB9A (0.64) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL10866984 | 0.92 | RAB9A (0.61) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL31490600 | 0.92 | RAB9A (0.61) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL30883993 | 0.92 | RAB9A (0.61) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL31365172 | 0.92 | RAB9A (0.61) | RAB9ANPC1CYP3A4CYP1A2AR | |
| SCHEMBL34463709 | 0.92 | RAB9A (0.61) | RAB9ANPC1CYP3A4CYP1A2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022241-B2 | Processes for producing carbonic ester and producing polycarbonate | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20100004479-A1 | PROCESSES FOR PRODUCING CARBONIC ESTER AND PRODUCING POLYCARBONATE | NATIONAL INSTIT. OF ADVANCE INDUST SCIENCE AND TECH (JP) | 2010-01-07 | — | — | US | disclosed |
| US-7629431-B2 | Polycarbonate prepolymer for solid phase polymerization and process for producing polycarbonate | IDEMITSU KOSAN CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-7598411-B2 | Processes for producing carbonic ester and producing polycarbonate | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20080064847-A1 | Oxidative carbonylation; molecular weight control | IDEMISU KOSAN CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20050234259-A1 | Processes for producing carbonic ester and producing polycarbonate | NATIONAL INSTIT OF ADVANCE INDUST SCIENCE AND TECH (JP) | 2005-10-20 | — | — | US | disclosed |
| US-6399738-B1 | OXIDATIVE CARBONYLATION OF AROMATIC HYDROXY COMPOUND WITH CARBON MONOXIDE AND OXYGEN | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004479-A1 | PROCESSES FOR PRODUCING CARBONIC ESTER AND PRODUCING POLYCARBONATE | HPD, PAH, PCCA | ACHE 4053/4885RAB9A 2808/4885NPC1 3448/4885 |
| US-20050234259-A1 | Processes for producing carbonic ester and producing polycarbonate | HPD, PAH, PCCA | ACHE 4053/4885RAB9A 2808/4885NPC1 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.