Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL241599 | 0.90 | TDP1 (0.58) | TDP1ATML3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL10610842 | 0.86 | POLB (0.50) | TDP1L3MBTL1SMN1; SMN2PPARGALDH1A1 | |
| SCHEMBL10907508 | 0.85 | TDP1 (0.54) | TDP1ATML3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL8014179 | 0.85 | PTGDR2 (0.54) | TDP1TSHRNOTUMSMN1; SMN2KDM4E | |
| SCHEMBL2996036 | 0.84 | ATM (0.53) | TDP1ATML3MBTL1TSHRNOTUM | |
| SCHEMBL644115 | 0.82 | TDP1 (0.58) | TDP1ATML3MBTL1TSHRNOTUM | |
| SCHEMBL29941922 | 0.82 | TDP1 (0.58) | TDP1ATML3MBTL1TSHRNOTUM | |
| SCHEMBL4825104 | 0.82 | ALDH1A1 (0.53) | TDP1ATML3MBTL1TSHRKDM4E | |
| SCHEMBL31412759 | 0.82 | TDP1 (0.51) | TDP1ATML3MBTL1NOTUMSMN1; SMN2 | |
| SCHEMBL4628924 | 0.81 | POLB (0.58) | ATML3MBTL1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914334-A | Polyester copolymer | 阿凡田知识中心有限公司 | 2020-03-24 | — | — | CN | disclosed |
| US-8859803-B2 | Process for production of ketomalonic acid compounds or hydrates thereof | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2447243-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004443-A1 | PROCESS FOR PRODUCTION OF KETOMALONIC ACID COMPOUNDS OR HYDRATES THEREOF | ME1, CA6, ME3 | TDP1 4627/4885ATM 1905/4885L3MBTL1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.