Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417828 | 0.91 | HSD11B1 (0.41) | HSD11B1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL2415027 | 0.91 | PRKAB2 (0.33) | — | |
| SCHEMBL2413440 | 0.84 | KMT2A (0.42) | HSD11B1KMT2ASMN1; SMN2MAPTALOX5AP | |
| SCHEMBL2417511 | 0.81 | MMP3 (0.36) | — | |
| SCHEMBL2415051 | 0.79 | ALDH1A1 (0.45) | HSD11B1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL2411183 | 0.79 | MAPK8 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL2413824 | 0.76 | LMNA (0.32) | — | |
| SCHEMBL2413098 | 0.76 | HSD11B1 (0.39) | HSD11B1ITGB2ICAM1ITGALKMT2A | |
| SCHEMBL2416674 | 0.76 | NEK2 (0.32) | — | |
| SCHEMBL2414093 | 0.76 | KMT2A (0.43) | HSD11B1KMT2ASYKSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |