SCHEMBL24166

SCHEMBL24166

Clc1ccccc1OBOc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HPGD P15428 2/20 0.39
SLC6A4 P31645 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A3 Q01959 2/20 0.38
ALDH1A1 P00352 2/20 0.37
HTT P42858 2/20 0.37
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CXCL8 P10145 1/20 0.37
DPP4 P27487 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263719 0.80 ALDH1A1 (0.42) TSHRLMNASMN1; SMN2SLC6A4SLC6A2
SCHEMBL14925378 0.80 MEN1 (0.43) TSHRLMNASMN1; SMN2HPGDL3MBTL1
SCHEMBL521826 0.77 MRGPRX4 (0.40) TSHRLMNASMN1; SMN2SLC6A4SLC6A2
SCHEMBL2723162 0.77 ALDH1A1 (0.45) LMNASLC6A4SLC6A2SLC6A3ALDH1A1
SCHEMBL7769417 0.75 TSHR (0.53) TSHRLMNASMN1; SMN2HPGDSLC6A4
SCHEMBL1436765 0.75 HPGD (0.59) TSHRLMNASMN1; SMN2HPGDSLC6A4
SCHEMBL10935253 0.72
SCHEMBL17224442 0.72 KMT2A (0.38) SMN1; SMN2HPGDALDH1A1KMT2A
SCHEMBL4469317 0.72 SLC6A4 (0.37) SLC6A4SLC6A2SLC6A3KCNH2
SCHEMBL337001 0.72 SLC6A4 (0.42) SMN1; SMN2SLC6A4L3MBTL1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 847 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978389-A Boron-containing oligomer for aging-resistant high-transparency addition-type silicon rubber, and preparation method and application thereof 中国科学院化学研究所 2025-05-13 CN claimed
CN-109180499-B Preparation method of rasagiline mesylate and intermediate thereof 上海博志研新药物技术有限公司 2021-04-30 CN claimed
CN-110760070-B Preparation method of functional compound RGO-IONP-PEG 海南省妇幼保健院 2020-11-10 CN claimed
CN-110760070-A Preparation method of functional compound RGO-IONP-PEG 海南省妇幼保健院 2020-02-07 CN claimed
US-10014475-B2 Graphene nanoribbons as semiconductors for organic thin film transistors EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2018-07-03 US claimed
US-20160087212-A1 GRAPHENE NANORIBBONS AS SEMICONDUCTORS FOR ORGANIC THIN FILM TRANSISTORS CRESTLINE DIRECT FINANCE, L.P. 2016-03-24 US claimed
US-9233967-B2 Process for the preparation of sitagliptin and intermediate compounds CIPLA LIMITED (IN) 2016-01-12 US claimed
US-20150197523-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND INTERMEDIATE COMPOUNDS CIPLA LIMITED (IN) 2015-07-16 US claimed
EP-2882752-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND INTERMEDIATE COMPOUNDS Cipla Limited (IN) 2015-06-17 EP claimed
US-8921299-B2 Detergents having acceptable color THE PROCTER & GAMBLE COMPANY (US) 2014-12-30 US claimed
WO-2014171931-A1 GRAPHENE NANORIBBONS AS SEMICONDUCTORS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-10-23 WO claimed
WO-2014023930-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND INTERMEDIATE COMPOUNDS CIPLA LIMITED (IN) 2014-02-13 WO claimed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO claimed
EP-3911640-B1 PCSK9 INHIBITORS FOR USE IN THERAPY, ESPECIALLY THE TREATMENT OF CARDIOVASCULAR DISEASE ASTRAZENECA AB (SE) 2026-05-13 EP disclosed
CN-122028604-A Organic electroluminescent element and electronic device including the same 出光兴产株式会社 2026-05-12 CN disclosed
US-12624032-B2 Pyrido[2,3-d]pyrimidin-7-ones and related compounds as inhibitors of protein kinases UNIVERSITY OF HOUSTON SYSTEM (US) 2026-05-12 US disclosed
WO-2000066571-A1 CYCLOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed
WO-2000066164-A1 CONTRACEPTIVE COMPOSITIONS CONTAINING ANTIPROGESTINIC AND PROGESTINIC AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed
WO-2000066570-A1 CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS AMERICAN HOME PRODUCTS CORPORATION (US) 2000-11-09 WO disclosed
WO-1995005081-A1 BIOCIDAL COMPOSITIONS CONTAINING ORGANOBORON COMPOUNDS U.S. BORAX INC. (US) 1995-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10014475-B2 Graphene nanoribbons as semiconductors for organic thin film transistors STRA6, OR10J3, EPCAM TSHR 1452/4885LMNA 4404/4885SMN1; SMN2 3246/4885
US-20150197523-A1 PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND INTERMEDIATE COMPOUNDS DPP4, DPP7, DPP9 TSHR 803/4885LMNA 2767/4885SMN1; SMN2 879/4885
US-12624032-B2 Pyrido[2,3-d]pyrimidin-7-ones and related compounds as inhibitors of protein kinases RIPK2, RIPK1, RIPK4 TSHR 1679/4885LMNA 790/4885SMN1; SMN2 936/4885
US-20160087212-A1 GRAPHENE NANORIBBONS AS SEMICONDUCTORS FOR ORGANIC THIN FILM TRANSISTORS STRA6, OR10J3, EPCAM TSHR 1452/4885LMNA 4404/4885SMN1; SMN2 3246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.