Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645461 | 0.80 | NPC1 (0.70) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL16180694 | 0.73 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL21593633 | 0.73 | RAB9A (1.00) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL22692996 | 0.70 | MAPT (0.62) | MEN1KMT2AALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL4987866 | 0.66 | NPC1 (0.73) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL22926452 | 0.65 | RAB9A (0.47) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL18407399 | 0.65 | RAB9A (0.76) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL24723929 | 0.65 | HDAC3 (0.51) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22645323 | 0.65 | HDAC3 (0.53) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL22662529 | 0.65 | HDAC3 (0.53) | RAB9ANPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214556-B1 | Method of treating colorectal cancer | KING ABDULAZIZ UNIVERSITY (SA) | 2022-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11214556-B1 | Method of treating colorectal cancer | APC, SLC10A2, FOLR1 | RAB9A 2623/4885NPC1 343/4885MEN1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.