Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 6/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.68 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.68 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19079785 | 0.98 | RXFP1 (0.78) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19079783 | 0.91 | PDE4D (0.80) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19079784 | 0.89 | POLB (0.71) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19079788 | 0.89 | L3MBTL1 (0.77) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19079843 | 0.83 | PDE4D (0.87) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL13856555 | 0.81 | POLB (1.00) | ALDH1A1SMN1; SMN2POLBTDP1RECQL | |
| SCHEMBL19088672 | 0.81 | RXFP1 (0.85) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL19079780 | 0.81 | RXFP1 (0.67) | RXFP1ALDH1A1SMN1; SMN2PDE4DTP53 | |
| SCHEMBL14478791 | 0.81 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2POLBTDP1RECQL | |
| SCHEMBL19079779 | 0.80 | RXFP1 (0.84) | RXFP1ALDH1A1SMN1; SMN2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472185-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2025-11-18 | — | — | US | claimed |
| US-20260041687-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | PENN STATE RES FOUND (US) | 2026-02-12 | — | — | US | disclosed |
| US-12472185-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2025-11-18 | — | — | US | disclosed |
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | THE PENN STATE RESEARCH FOUNDATION | 2023-06-29 | — | — | US | disclosed |
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | THE PENN STATE RESEARCH FOUNDATION | 2023-06-29 | — | — | US | disclosed |
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | THE PENN STATE RESEARCH FOUNDATION | 2023-06-29 | — | — | US | disclosed |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-05-23 | — | — | US | disclosed |
| US-20210401843-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | THE PENN STATE RESEARCH FOUNDATION | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260041687-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | VDAC1, VDAC3, VIL1 | RXFP1 2629/4885ALDH1A1 534/4885SMN1; SMN2 1847/4885 |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | CLPP, SPOUT1, CASP3 | RXFP1 4086/4885ALDH1A1 942/4885SMN1; SMN2 3817/4885 |
| US-20210401843-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | CLPP, SPOUT1, CASP3 | RXFP1 4086/4885ALDH1A1 942/4885SMN1; SMN2 3817/4885 |
| US-12472185-B2 | Methods for killing antibiotic tolerant bacteria | CLPP, SPOUT1, CASP3 | RXFP1 4086/4885ALDH1A1 942/4885SMN1; SMN2 3817/4885 |
| US-20230201206-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | CLPP, SPOUT1, CASP3 | RXFP1 4086/4885ALDH1A1 942/4885SMN1; SMN2 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.