Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423153 | 0.83 | DPP4 (0.45) | TAAR1HTR2AHRH1CYP2D6TDP1 | |
| SCHEMBL24176561 | 0.79 | ALOX5 (0.47) | KDM4EALDH1A1TAAR1HTR2AHRH1 | |
| SCHEMBL8433241 | 0.79 | ALOX5 (0.47) | KDM4EALDH1A1TAAR1HTR2AHRH1 | |
| SCHEMBL24176558 | 0.79 | ALOX5 (0.47) | KDM4EALDH1A1TAAR1HTR2AHRH1 | |
| SCHEMBL14024643 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1TAAR1HTR2AHRH1 | |
| SCHEMBL23578509 | 0.77 | LMNA (0.45) | KDM4EALDH1A1TAAR1HTR2AHRH1 | |
| SCHEMBL5424451 | 0.72 | HTR2A (0.50) | KDM4EALDH1A1HTR2AHRH1AOC3 | |
| SCHEMBL674996 | 0.72 | CHRNA7 (0.59) | KDM4EALDH1A1HTR2AHRH1AOC3 | |
| SCHEMBL1760781 | 0.72 | OPRD1 (0.50) | ALDH1A1TAAR1HTR2AHRH1AOC3 | |
| SCHEMBL17586565 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1TAAR1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-20220002328-A1 | SILYL-BIARYL PHOSPHORAMIDITES AND METHODS OF MAKING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | PAICS, PGLS, SCLY | KDM4E 3107/4885ALDH1A1 3857/4885TAAR1 4177/4885 |
| US-20220002328-A1 | SILYL-BIARYL PHOSPHORAMIDITES AND METHODS OF MAKING | PAICS, PGLS, SCLY | KDM4E 3107/4885ALDH1A1 3857/4885TAAR1 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.