Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | PRKCG | P05129 | 3/20 | 0.43 |
| ▸ | PRKCB | P05771 | 3/20 | 0.43 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | PRKCH | P24723 | 3/20 | 0.43 |
| ▸ | PRKCI | P41743 | 3/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | PRKACG | P22612 | 2/20 | 0.43 |
| ▸ | PRKACB | P22694 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23810345 | 1.00 | P2RX7 (0.45) | P2RX7NR3C1PRKD3PRKCGPRKCB | |
| SCHEMBL24178116 | 0.88 | P2RX7 (0.42) | P2RX7NR3C1PRKD3PRKCGPRKCB | |
| SCHEMBL23810360 | 0.88 | P2RX7 (0.42) | P2RX7NR3C1PRKD3PRKCGPRKCB | |
| SCHEMBL23810416 | 0.88 | P2RX7 (0.44) | P2RX7PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL24177984 | 0.88 | P2RX7 (0.44) | P2RX7PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL6977460 | 0.85 | STK33 (0.38) | P2RX7NR3C1PRKD3PRKCZPRKCD | |
| SCHEMBL6977452 | 0.85 | STK33 (0.38) | P2RX7NR3C1PRKD3PRKCZPRKCD | |
| SCHEMBL14520577 | 0.85 | STK33 (0.38) | P2RX7NR3C1PRKD3PRKCZPRKCD | |
| SCHEMBL14257036 | 0.84 | NR3C1 (0.33) | P2RX7NR3C1 | |
| SCHEMBL14257024 | 0.84 | SSTR4 (0.34) | P2RX7NR3C1MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) | 2022-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | ROCK1, RHOA, ROCK2 | P2RX7 2362/4885NR3C1 3111/4885PRKD3 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.