Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.33 |
| ▸ | ATR | Q13535 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25917467 | 0.92 | RXRA (0.36) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL25918087 | 0.82 | MAPK8 (0.36) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL30724136 | 0.81 | ALOX5AP (0.39) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL25917465 | 0.81 | RXRA (0.37) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL25918088 | 0.77 | RXRA (0.38) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL30723809 | 0.76 | RXRA (0.46) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL25917394 | 0.76 | RXRA (0.39) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL24179486 | 0.76 | CYP4F2 (0.39) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL25917464 | 0.75 | RXRA (0.40) | RXRARXRBRXRGMAPK8MAPK9 | |
| SCHEMBL7272765 | 0.72 | RXRA (0.39) | RXRARXRBRXRGMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242507-A1 | INDAZOLE-FUSED CYCLIC COMPOUND | Zhejiang Yangli Pharmaceutical Technology Co., Ltd. (CN) | 2023-08-03 | — | — | US | disclosed |
| WO-2022001971-A1 | INDAZOLE-FUSED CYCLIC COMPOUND | 南京明德新药研发有限公司 | 2022-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242507-A1 | INDAZOLE-FUSED CYCLIC COMPOUND | SLC5A11, CYP11B2, CYP4F11 | RXRA 3699/4885RXRB 3804/4885RXRG 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.