Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426965 | 0.86 | CD274 (0.32) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24180234 | 0.78 | MEN1 (0.33) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24180238 | 0.78 | EIF4A1 (0.38) | ALDH1A1CYP3A4HPGDMAPK1F2 | |
| SCHEMBL24180246 | 0.77 | PPARG (0.34) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24426931 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24180152 | 0.77 | CYP3A4 (0.33) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24426924 | 0.76 | CYP3A4 (0.40) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24180282 | 0.76 | CYP3A4 (0.40) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 | |
| SCHEMBL24180202 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10DRD2 | |
| SCHEMBL24426991 | 0.74 | CYP19A1 (0.34) | ALDH1A1CYP3A4KDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998257-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2022-05-18 | — | — | EP | disclosed |
| EP-3418273-B1 | FLAVAGLINE DERIVATIVES | PF MEDICAMENT (FR) | 2022-01-12 | — | — | EP | disclosed |