SCHEMBL24183992

SCHEMBL24183992

O=C1OC(=O)c2cc3c(cc21)-c1cc2c(cc1C31c3cc(I)ccc3-c3ccc(I)cc31)C(=O)OC2=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.40
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TGM2 P21980 1/20 0.33
CES1 P23141 1/20 0.33
CA1 P00915 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24184097 0.94 TDP1 (0.38) TDP2CA12CA7ALDH1A1ALOX15
SCHEMBL22000344 0.83 ALOX15 (0.42) ALDH1A1ALOX15TDP1
SCHEMBL24183984 0.80 TDP1 (0.48) ALDH1A1ALOX15TDP1
SCHEMBL19695980 0.80 TDP1 (0.48) ALDH1A1ALOX15TDP1
SCHEMBL24183981 0.79 AKR1A1 (0.42) CA7ALDH1A1ALOX15TDP1CA1
SCHEMBL24184098 0.79 PPOX (0.43) TDP2CA12CA7ALDH1A1ALOX15
SCHEMBL24184226 0.79 ELANE (0.39) CA12CA7ALDH1A1ALOX15TDP1
SCHEMBL6864497 0.79 TDP2 (0.41) TDP2TGM2CES1
SCHEMBL2207735 0.77 ALOX15 (0.52) TDP2CA12CA7ALDH1A1ALOX15
SCHEMBL24184255 0.76 PDK2 (0.42) CA7ALDH1A1CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530228-B2 Tetracarboxylic acid dianhydride and method for preparing the same SK INNOVATION CO., LTD. (KR) 2022-12-20 US disclosed
US-20220009943-A1 Tetracarboxylic Acid Dianhydride and Method for Preparing the Same SK INNOVATION CO., LTD. (KR) 2022-01-13 US disclosed
US-20220010071-A1 Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof SK IE TECHNOLOGY CO., LTD. (KR) 2022-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220009943-A1 Tetracarboxylic Acid Dianhydride and Method for Preparing the Same TET1, HDHD5, TET3 TDP2 1286/4885CA12 180/4885CA7 253/4885
US-11530228-B2 Tetracarboxylic acid dianhydride and method for preparing the same TET1, HDHD5, TET3 TDP2 1286/4885CA12 180/4885CA7 253/4885
US-20220010071-A1 Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof PARG, PARN, PUF60 TDP2 1665/4885CA12 1405/4885CA7 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.