Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24187458 | 0.84 | MTNR1A (0.46) | MAPTMTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL15563812 | 0.84 | DRD2 (0.44) | MAPTALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL16150685 | 0.82 | MAPT (0.47) | MAPTALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL24187332 | 0.81 | KDM4E (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2CRHBP | |
| SCHEMBL30104792 | 0.81 | ADORA3 (0.39) | MAPTMTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL5353301 | 0.81 | SERPINE1 (0.36) | MAPTALDH1A1KDM4ESMN1; SMN2NOD2 | |
| SCHEMBL5353304 | 0.81 | SERPINE1 (0.36) | MAPTALDH1A1KDM4ESMN1; SMN2NOD2 | |
| SCHEMBL20141699 | 0.81 | MTNR1A (0.59) | MAPTALDH1A1MTNR1AMTNR1BKDM4E | |
| SCHEMBL29878502 | 0.80 | ADORA3 (0.40) | MAPTMTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL29153650 | 0.80 | MTNR1A (0.42) | MAPTALDH1A1MTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007866-A1 | FUSED TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |