Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 7/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29878502 | 0.87 | ADORA3 (0.40) | ADORA3ADORA2ABRD4STING1DYRK1A | |
| SCHEMBL30104845 | 0.83 | STING1 (0.50) | BRD4STING1 | |
| SCHEMBL29153650 | 0.83 | MTNR1A (0.42) | STING1MTNR1AMTNR1BKDM4ECRHBP | |
| SCHEMBL24640541 | 0.81 | POLB (0.41) | ADORA3ADORA2ABRD4KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30104789 | 0.81 | KDM4E (0.43) | KDM4ECRHBPCRHR2SMN1; SMN2QRFPR | |
| SCHEMBL24187331 | 0.81 | MAPT (0.39) | ADORA3ADORA2AMTNR1AMTNR1BKDM4E | |
| SCHEMBL16150685 | 0.80 | MAPT (0.47) | BRD4DYRK1AMTNR1AMTNR1BKDM4E | |
| SCHEMBL20141699 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BKDM4ECRHBPCRHR2 | |
| SCHEMBL30681405 | 0.79 | KDM4E (0.37) | KDM4EQRFPRMAPT | |
| SCHEMBL27341116 | 0.79 | HPGD (0.43) | ADORA3ADORA2ABRD4STING1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |