Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.69 |
| ▸ | SCN1A | P35498 | 1/20 | 0.69 |
| ▸ | SCN4A | P35499 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.69 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.69 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.69 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.69 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27233049 | 0.94 | ALDH1A1 (0.56) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| SCHEMBL24193557 | 0.87 | CYP2C9 (0.63) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL5499612 | 0.83 | CYP2C9 (1.00) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL3440 | 0.83 | CYP2C9 (1.00) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL2140317 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL1461588 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL157671 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL2905857 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL10406406 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A | |
| Phenytoin SCHEMBL5160618 | 0.81 | CYP2C9 (0.96) | MAPTALDH1A1CYP2C9CACNA1FHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009875-A1 | NITRATION | NOS1, NOS2, NOS3 | MAPT 3137/4885ALDH1A1 2335/4885CYP2C9 117/4885 |
| US-11655203-B2 | Nitration | NOS1, NOS2, NOS3 | MAPT 3137/4885ALDH1A1 2335/4885CYP2C9 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.