Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.54 |
| ▸ | TLR4 | O00206 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874507 | 0.87 | NPC1 (0.51) | APPTLR4XDHNLRP3ALDH1A1 | |
| SCHEMBL29879187 | 0.87 | NPC1 (0.51) | APPTLR4XDHNLRP3ALDH1A1 | |
| SCHEMBL29593205 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1CA12CA1CA3 | |
| SCHEMBL1656100 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1CA12CA1CA3 | |
| SCHEMBL9306595 | 0.81 | F2RL3 (0.46) | APPKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7975021 | 0.81 | APP (0.57) | APPKDM4EALDH1A1CA12CA1 | |
| SCHEMBL22382386 | 0.81 | APP (0.60) | APPF2RL3 | |
| SCHEMBL6791597 | 0.80 | APP (0.59) | APPTLR4XDHNLRP3KDM4E | |
| SCHEMBL17153954 | 0.79 | GLA (0.54) | APPKDM4EALDH1A1CA12HPGD | |
| SCHEMBL558021 | 0.79 | PIK3CG (0.56) | APPTLR4XDHNLRP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4587200-A | Photopolymerizable composition comprising an acridine and a heterocyclic thiol compound as a photopolymerization initiator and a photographic process using said photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-06 | — | — | US | claimed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240051952-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-02-15 | — | — | US | disclosed |
| US-20220177460-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2022-06-09 | — | — | US | disclosed |
| US-20220177460-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2022-06-09 | — | — | US | disclosed |
| EP-3952990-A1 | HMOX1 INDUCERS | Mitobridge, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113874074-A | HMOX1 inducers | 米托布里奇公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-104530037-B | Triazine heterocyclic compound with nematicidal activity and preparation method and application thereof | 华东理工大学 | 2020-12-18 | — | — | CN | disclosed |
| EP-0660830-A1 | BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1995-07-05 | — | — | EP | disclosed |
| EP-0621271-A1 | Benzoxazole derivatives and their use as serotonin 5-HT3 receptor antagonists | MEIJI SEIKA KAISHA LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| WO-1994006782-A1 | BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |
| US-5273988-A | 2-(3,4,4,-trifluorobutenylmercapto) alkoxy or nitro benzoxazoyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-28 | — | — | US | disclosed |
| EP-0532722-A1 | BENZOXAIOLE DERIVATIVES | ZENECA LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1992017463-A1 | BENZOXAIOLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0507464-A1 | Benzoxazole derivatives | ZENECA LIMITED (GB) | 1992-10-07 | — | — | EP | disclosed |
| US-4587200-A | Photopolymerizable composition comprising an acridine and a heterocyclic thiol compound as a photopolymerization initiator and a photographic process using said photopolymerizable composition | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-06 | — | — | US | disclosed |
| EP-0129506-A2 | Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids | CIBA-GEIGY AG (CH) | 1984-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | APP 3212/4885TLR4 1903/4885XDH 97/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | APP 3020/4885TLR4 1852/4885XDH 82/4885 |
| US-20240051952-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, QSOX1 | APP 2576/4885TLR4 1312/4885XDH 63/4885 |
| US-20220177460-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | APP 3020/4885TLR4 1852/4885XDH 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.