Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8257893 | 0.82 | ALDH1A1 (0.42) | ALDH1A1POLBALOX5SCN9ATDO2 | |
| SCHEMBL31662970 | 0.82 | RAD51 (0.44) | ALDH1A1POLBALOX5TDO2CMA1 | |
| SCHEMBL18640602 | 0.82 | ALDH1A1 (0.38) | ALDH1A1POLBALOX5SCN9ATDO2 | |
| SCHEMBL16965435 | 0.82 | TDO2 (0.39) | ALDH1A1POLBALOX5SCN9ATDO2 | |
| SCHEMBL15596119 | 0.79 | DRD2 (0.48) | ALDH1A1POLBMAPTCYP1A2CYP2D6 | |
| SCHEMBL38658736 | 0.78 | THRB (0.40) | ALDH1A1POLBALOX5SCN9ATDO2 | |
| SCHEMBL305860 | 0.78 | ALDH1A1 (0.55) | ALDH1A1POLBALOX5SCN9AMAPT | |
| SCHEMBL8250866 | 0.77 | F10 (0.47) | ALDH1A1SCN9ATDO2F10MAPT | |
| SCHEMBL31129874 | 0.77 | MEN1 (0.41) | ALDH1A1POLBMAPTKDM4ECYP3A4 | |
| SCHEMBL5056229 | 0.76 | ALOX5 (0.50) | ALDH1A1POLBALOX5SCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |