Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656155 | 0.86 | KDM4E (0.53) | KDM4EGAAMAPTKIF11POLB | |
| SCHEMBL17546483 | 0.80 | ADRB2 (0.41) | KDM4EMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL14955802 | 0.80 | ADRB2 (0.41) | KDM4EMAPTPOLBNPC1RAB9A | |
| SCHEMBL30417281 | 0.75 | ALDH1A1 (0.50) | KDM4EGAANPC1RAB9AALDH1A1 | |
| SCHEMBL22960107 | 0.73 | MAPT (0.52) | KDM4EGAAMAPTKIF11POLB | |
| SCHEMBL30720010 | 0.73 | MAPT (0.52) | KDM4EGAAMAPTKIF11POLB | |
| SCHEMBL22780741 | 0.73 | MAOA (0.48) | KDM4EGAAMAPTKIF11POLB | |
| SCHEMBL14357355 | 0.73 | KIF11 (0.61) | KDM4EKIF11POLBALDH1A1KMT2A | |
| SCHEMBL112570 | 0.72 | POLB (0.55) | KDM4EGAAMAPTPOLBNPC1 | |
| SCHEMBL2593638 | 0.72 | POLB (0.55) | KDM4EGAAMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |