Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30297103 | 0.75 | ADRB1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20037562 | 0.75 | ADRB1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8250845 | 0.72 | HTR6 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL24920523 | 0.72 | ADRB1 (0.51) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL24198477 | 0.72 | KDM4E (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30484798 | 0.72 | NCF1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20255446 | 0.72 | HTR7 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL18291599 | 0.72 | NCF1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20249187 | 0.72 | HTR6 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL26092566 | 0.71 | KDM4E (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795158-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2023-10-24 | — | — | US | disclosed |
| US-20220009901-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795158-B2 | Chemical compounds | CYP11B2, CYP11B1, CYP4B1 | HTR3E 3239/4885HTR3B 2436/4885HTR3A 3394/4885 |
| US-20220009901-A1 | CHEMICAL COMPOUNDS | CYP11B2, CYP11B1, CYP4B1 | HTR3E 3239/4885HTR3B 2436/4885HTR3A 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.