Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198615 | 0.86 | MAPT (0.37) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL27692288 | 0.77 | RAB9A (0.54) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| Iodide SCHEMBL1286904 | 0.76 | RAB9A (0.53) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL10033645 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2APOLBL3MBTL1RAB9A | |
| SCHEMBL12650603 | 0.71 | NR1H4 (0.46) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL1996357 | 0.71 | SIGMAR1 (0.57) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL27003089 | 0.69 | RAB9A (0.68) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL23332264 | 0.68 | NPC1 (0.56) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL10033639 | 0.68 | NAPRT (0.58) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL516844 | 0.67 | RAB9A (0.65) | MEN1KMT2AMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220009884-A1 | MITOCHONDRIAL ACTIVITY INHIBITORS TARGETING TUMORAL METABOLISM | UNIVERSITE GRENOBLE ALPES (FR) | 2022-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009884-A1 | MITOCHONDRIAL ACTIVITY INHIBITORS TARGETING TUMORAL METABOLISM | NDUFAB1, CYP11B1, ME3 | MEN1 2078/4885KMT2A 3390/4885MAPT 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.