Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455699 | 0.79 | TBXAS1 (0.49) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL21455539 | 0.75 | TBXAS1 (0.36) | TBXAS1PKMGAAHPGDTACR1 | |
| SCHEMBL7890168 | 0.74 | TBXAS1 (0.59) | TBXAS1PKMGAACYP4F2CYP4A11 | |
| SCHEMBL1792326 | 0.74 | TSHR (0.55) | TBXAS1PKMSMN1; SMN2MEN1KMT2A | |
| SCHEMBL68340 | 0.73 | PKM (0.60) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL29346996 | 0.73 | ALDH1A1 (0.44) | TBXAS1PKMCYP4F2CYP4A11HPGD | |
| SCHEMBL23229267 | 0.73 | TBXAS1 (0.51) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL18050410 | 0.72 | TBXAS1 (0.48) | TBXAS1PKMCYP4F2CYP4A11HPGD | |
| SCHEMBL28392981 | 0.72 | TBXAS1 (0.50) | TBXAS1PKMCYP4F2CYP4A11HPGD | |
| SCHEMBL18050464 | 0.72 | CYP4F2 (0.50) | TBXAS1PKMCYP4F2CYP4A11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |