Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436317 | 0.75 | CRHR1 (0.37) | LMNAALDH1A1HTTNLRP3MAPT | |
| SCHEMBL20436310 | 0.74 | NLRP3 (0.36) | LMNAALDH1A1HTTNLRP3MAPT | |
| SCHEMBL24200370 | 0.73 | PARP14 (0.44) | LMNAALDH1A1HTTMAPTTHRB | |
| SCHEMBL20436314 | 0.73 | ITGB1 (0.37) | LMNAALDH1A1HTTNLRP3MAPT | |
| SCHEMBL4403976 | 0.72 | ITGB1 (0.55) | ALDH1A1HTTMAPTL3MBTL1ITGB1 | |
| SCHEMBL20436323 | 0.70 | MAPT (0.49) | LMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL20458582 | 0.70 | CHRM3 (0.35) | LMNAALDH1A1MAPTTHRBL3MBTL1 | |
| SCHEMBL20436324 | 0.69 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL24404997 | 0.66 | MAPT (0.32) | LMNAALDH1A1NLRP3MAPTL3MBTL1 | |
| SCHEMBL30613917 | 0.64 | NR3C1 (0.36) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3358346-B1 | ENANTIOMER ANALYSIS METHOD | AJINOMOTO KK (JP) | 2022-01-19 | — | — | EP | disclosed |