Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952289 | 0.85 | KIF11 (0.65) | USP2RAB9AKIF11CYP19A1 | |
| SCHEMBL7929536 | 0.84 | KCNN4 (0.44) | USP2RAB9ACYP19A1MEN1KMT2A | |
| SCHEMBL2309836 | 0.79 | USP2 (1.00) | USP2RAB9AKIF11LTA4HL3MBTL1 | |
| SCHEMBL26294659 | 0.78 | ALDH1A1 (0.55) | USP2RAB9AKIF11MAPK14CYP19A1 | |
| SCHEMBL6000168 | 0.76 | USP2 (0.59) | USP2RAB9AKIF11LTA4HMAPK14 | |
| SCHEMBL11684104 | 0.76 | USP2 (0.70) | USP2RAB9AKIF11LTA4HL3MBTL1 | |
| SCHEMBL32673682 | 0.76 | RAB9A (0.44) | USP2RAB9AKIF11LTA4HCYP19A1 | |
| SCHEMBL173641 | 0.73 | KIF11 (0.70) | USP2RAB9AKIF11CYP19A1 | |
| SCHEMBL168026 | 0.73 | ALDH1A1 (0.53) | USP2RAB9AKIF11TAAR1 | |
| SCHEMBL9440519 | 0.73 | APP (0.41) | USP2RAB9AMAPK14CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117254-A1 | PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR | PROSIDION LIMITED (GB) | 2011-09-29 | — | — | WO | disclosed |