Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26732901 | 1.00 | SOS1 (0.43) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL31394743 | 0.88 | SOS1 (0.51) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL24801995 | 0.82 | SOS1 (0.47) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL23526138 | 0.82 | SOS1 (0.47) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL30451450 | 0.82 | CA12 (0.39) | TSHRKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL26732899 | 0.82 | CA12 (0.39) | TSHRKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL26732898 | 0.82 | CA12 (0.39) | TSHRKDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL1044961 | 0.80 | SOS1 (0.46) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL31079873 | 0.80 | SOS1 (0.50) | SOS1LMNATSHRNPSR1KDM4E | |
| SCHEMBL365953 | 0.80 | SOS1 (0.50) | SOS1LMNATSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357162-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357162-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | TENVIE THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| CN-116804004-A | Compounds as DHODH inhibitors | 南京征祥医药有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-20230271943-A1 | COMPOUNDS AS DHODH INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| US-20230271943-A1 | COMPOUNDS AS DHODH INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-08-31 | — | — | US | disclosed |
| CN-116457343-A | Compounds as DHODH inhibitors | 南京征祥医药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4196125-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | Denali Therapeutics Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| CN-116261456-A | Compounds, compositions, and methods | 戴纳立制药公司 | 2023-06-13 | — | — | CN | disclosed |
| WO-2022036204-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | DENALI THERAPEUTICS INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022012548-A1 | COMPOUNDS AS DHODH INHIBITORS | NANJING ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2022-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357162-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | NLRP3, NLRP1, NOD1 | SOS1 1541/4885LMNA 1886/4885TSHR 4284/4885 |
| US-20230271943-A1 | COMPOUNDS AS DHODH INHIBITORS | DHODH, DLD, DHRS9 | SOS1 2692/4885LMNA 3421/4885TSHR 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.