Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159138 | 0.95 | LMNA (0.58) | LMNACYP1A2ALDH1A1MAPTMAPK1 | |
| SCHEMBL21725258 | 0.95 | LMNA (0.58) | LMNACYP1A2ALDH1A1MAPTMAPK1 | |
| SCHEMBL26073642 | 0.93 | LMNA (0.43) | LMNACYP1A2ALDH1A1MAPTMAPK1 | |
| SCHEMBL21725260 | 0.93 | LMNA (0.61) | LMNACYP1A2ALDH1A1MAPTMAPK1 | |
| SCHEMBL29308241 | 0.93 | LMNA (0.61) | LMNACYP1A2ALDH1A1MAPTMAPK1 | |
| SCHEMBL24205655 | 0.92 | GAA (0.44) | LMNACYP1A2ALDH1A1GAAMGAM | |
| SCHEMBL9656170 | 0.89 | ALDH1A1 (0.41) | LMNACYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL9656163 | 0.89 | ALDH1A1 (0.41) | LMNACYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL25985792 | 0.85 | MGAM (0.39) | LMNACYP1A2ALDH1A1GAAMAPT | |
| SCHEMBL23159139 | 0.81 | LMNA (0.59) | LMNAALDH1A1MAPTMAPK1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917264-A | Process for preparing hydroxybutyric acid carboxylic ester | 凯托利皮克斯治疗有限责任公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230303478-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES | KETOLIPIX THERAPEUTICS GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| US-20230303478-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES | KETOLIPIX THERAPEUTICS GMBH (DE) | 2023-09-28 | — | — | US | disclosed |
| EP-4146338-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES | KetoLipix Therapeutics GmbH (DE) | 2023-03-15 | — | — | EP | disclosed |
| WO-2022012765-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES | IOI OLEO GMBH (DE) | 2022-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303478-A1 | PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS OF HYDROXYBUTANOATES | HAO2, HSD17B12, HCAR3 | LMNA 3241/4885CYP1A2 231/4885ALDH1A1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.