Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014827 | 0.80 | KMT2A (0.46) | MEN1KMT2ANOTUMSMN1; SMN2LMNA | |
| SCHEMBL24209174 | 0.77 | SMN1; SMN2 (0.38) | MEN1KMT2ANOTUMSMN1; SMN2LMNA | |
| SCHEMBL22014833 | 0.68 | RAB9A (0.40) | MEN1KMT2ANOTUMSMN1; SMN2LMNA | |
| SCHEMBL22014825 | 0.68 | SMN1; SMN2 (0.38) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL24208966 | 0.67 | GAA (0.41) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL22014824 | 0.66 | CHRM1 (0.36) | MEN1KMT2ANOTUMSMN1; SMN2LMNA | |
| SCHEMBL24209125 | 0.65 | SMN1; SMN2 (0.34) | MEN1KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL24209303 | 0.65 | CYP1A2 (0.39) | MEN1KMT2ANOTUMSMN1; SMN2LMNA | |
| SCHEMBL22014835 | 0.65 | EIF4H (0.36) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL24209131 | 0.65 | KDM4E (0.39) | MEN1KMT2AALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017516-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017516-A1 | LOX INHIBITORS | LOXL1, LOX, LOXL2 | MEN1 3915/4885KMT2A 2212/4885NOTUM 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.