Sugi Predict

Sugi Predict / Compounds / SCHEMBL24216424

SCHEMBL24216424

SCHEMBL24216424

c1ccc(-c2ccc3c4ccccc4n(-c4ccc5oc6ccc(-c7nc(-c8ccccc8)nc(-c8ccc9c(c8)oc8ccccc89)n7)cc6c5c4)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 3/20 0.37
▸ PLA2G4A P47712 3/20 0.37
▸ CHEK2 O96017 1/20 0.36
▸ MMP12 P39900 2/20 0.35
▸ MMP13 P45452 1/20 0.35
▸ HCRTR1 O43613 1/20 0.34
▸ PTGER4 P35408 1/20 0.34
▸ KDM4E B2RXH2 3/20 0.33
▸ ATM Q13315 2/20 0.33
▸ NPC1 O15118 2/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ PLA2G10 O15496 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ AHR P35869 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24216543 0.99 MMP12 (0.36) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL24216508 0.98 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21883359 0.98 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21669202 0.98 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21883320 0.98 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL25926900 0.98 L3MBTL1 (0.35) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21573675 0.97 L3MBTL1 (0.34) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21191897 0.97 CHEK2 (0.38) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21668702 0.96 PLA2G2A (0.33) PLA2G2APLA2G4ACHEK2MMP12MMP13
SCHEMBL21573697 0.96 PRKDC (0.33) PLA2G2APLA2G4ACHEK2MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 — — US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 — — US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 — — US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 — — US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 — — US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 — — US disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 PLA2G2A 3486/4885PLA2G4A 4142/4885CHEK2 3865/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 PLA2G2A 3903/4885PLA2G4A 4050/4885CHEK2 3253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.