Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158758 | 0.93 | CA2 (0.47) | CA2CYP4A11LTA4HEPHX2TDP1 | |
| SCHEMBL3585945 | 0.91 | CA2 (0.48) | CA2CYP4A11LTA4HEPHX2TDP1 | |
| SCHEMBL7167586 | 0.91 | CA2 (0.48) | CA2CYP4A11LTA4HEPHX2TDP1 | |
| Ammonia Solution, Strong SCHEMBL28350189 | 0.89 | CA2 (0.47) | CA2CYP4A11LTA4HEPHX2TDP1 | |
| SCHEMBL241799 | 0.84 | — | — | |
| SCHEMBL11803736 | 0.84 | MAOA (0.40) | SLC6A3L3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL11690401 | 0.81 | SIGMAR1 (0.41) | SLC6A3KDM4EALDH1A1LMNAESR1 | |
| SCHEMBL239040 | 0.81 | CA2 (0.60) | CA2CYP4A11LTA4HEPHX2TDP1 | |
| SCHEMBL28429295 | 0.81 | CA2 (0.46) | CA2CYP4A11LTA4HEPHX2CYP4F2 | |
| SCHEMBL5128402 | 0.79 | SIGMAR1 (0.47) | SLC6A3ADRA1AL3MBTL1ADORA3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116622335-A | High temperature resistant organosilicon pressure sensitive adhesive | 斯迪克新型材料（江苏）有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-111527084-B | Isofuranone compounds useful as HPK1 inhibitors | 百时美施贵宝公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116285769-A | Organosilicon pressure-sensitive adhesive tape and preparation method thereof | 斯迪克新型材料（江苏）有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-107325270-A | A kind of fire-retardant sulphonate-base PEPA of Halogen copoly type and preparation method thereof | 四川东材科技集团股份有限公司 | 2017-11-07 | — | — | CN | claimed |
| WO-2017034377-A1 | PYRIDOPYRIMIDINONE COMPOUNDS FOR MODULATING THE CATALYTIC ACTIVITY OF HISTONE LYSINE DEMETHYLASES (KDMS) | DONG-A ST CO., LTD. (KR) | 2017-03-02 | — | — | WO | claimed |
| US-20170057955-A1 | Pyridopyrimidinone Compounds for Modulating the Catalytic Activity of Histone Lysine Demethylases (KDMs) | DONG-A ST CO., LTD. (KR) | 2017-03-02 | — | — | US | claimed |
| CN-103739832-B | A kind of manufacture method of cationic dye capable of dyeing fire retardant polyester resin | SICHUAN DONGCAI TECHNOLOGY GROUP CO., LTD. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-104861492-A | Halogen-free flame retardation PTT polyester and preparation method therefor | QINGDAO XINZHAN PLASTIC CO LTD | 2015-08-26 | — | — | CN | claimed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | claimed |
| CN-103044673-B | Preparation method of reaction type halogen-free phosphorous flame retardant polyester polyol | SICHUAN DONGFANG INSULATING MATERIAL CO LTD | 2014-11-05 | — | — | CN | claimed |
| EP-1809473-A2 | PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-07-25 | — | — | EP | claimed |
| CN-1984775-A | Method for preparing redox-active polymers on surfaces | UNIV CALIFORNIA (US) | 2007-06-20 | — | — | CN | claimed |
| WO-2005086826-A2 | PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES | THE REGENTS OF THE UNIVERSITY (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050207208-A1 | Situ patterning of electrolyte for molecular information storage devices | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-09-22 | — | — | US | claimed |
| WO-2005017953-A2 | IN SITU PATTERNING OF ELECTROLYTE FOR MOLECULAR INFORMATION STORAGE DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-02-24 | — | — | WO | claimed |
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2004-09-16 | — | — | US | claimed |
| CN-1479715-A | Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils | ��ķ�ɷ�����˾ | 2004-03-03 | — | — | CN | claimed |
| EP-1255726-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8 INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.P.A. (IT) | 2002-11-13 | — | — | EP | claimed |
| WO-2001058852-A2 | (R)-2-ARYL-PROPIONAMIDES, USEFUL IN THE INHIBITION OF IL-8-INDUCED CHEMIOTAXIS OF NEUTROPHILS | Dompé S.p.A. (IT) | 2001-08-16 | — | — | WO | claimed |
| US-6265345-B1 | BINDER RESIN; KETONE-IMINE DYE; CAPABLE OF PRODUCING A PICTURE IMAGE HAVING AN IMPROVED LIGHT-RESISTANT COLORFASTNESS. | DAI NIPPON PRINTING CO., LTD. (JP) | 2001-07-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181073-A1 | Amides, useful in the inhibition of il-8-induced chemotaxis of neutrophils | CXCL8, MMP8, CCR8 | CA2 2998/4885CYP4A11 656/4885LTA4H 901/4885 |
| US-20170057955-A1 | Pyridopyrimidinone Compounds for Modulating the Catalytic Activity of Histone Lysine Demethylases (KDMs) | KDM1B, KDM1A, KDM3B | CA2 2969/4885CYP4A11 1330/4885LTA4H 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.