Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968755 | 0.94 | TAAR1 (0.34) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL9562138 | 0.94 | TAAR1 (0.34) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL8496556 | 0.94 | TAAR1 (0.34) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL242277 | 0.90 | TAAR1 (0.38) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL816601 | 0.90 | GAA (0.39) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL30723203 | 0.90 | GAA (0.39) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL5718625 | 0.90 | GAA (0.39) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL29975298 | 0.90 | GAA (0.39) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL8082255 | 0.88 | GAA (0.38) | TAAR1GAAHSD17B10MPLAMY1A | |
| SCHEMBL8084715 | 0.88 | GAA (0.38) | TAAR1GAAHSD17B10MPLAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12544463-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | FIVE ELEVEN PHARMA INC. (US) | 2026-02-10 | — | — | US | disclosed |
| EP-4663637-A2 | NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION | Five Eleven Pharma Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| CN-114539243-B | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agent and pharmacological application thereof | 五一一制药股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115536580-A | Deuterium substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110678465-B | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-111517902-B | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114539243-A | Novel deuterium-substituted Positron Emission Tomography (PET) imaging agents and their pharmacological use | 五一一制药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20210346526-A1 | NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION | FIVE ELEVEN PHARMA INC. | 2021-11-11 | — | — | US | disclosed |
| US-11071794-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | FIVE ELEVEN PHARMA INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-10912849-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | FIVE ELEVEN PHARMA INC. (US) | 2021-02-09 | — | — | US | disclosed |
| WO-2010049819-A1 | USE OF 7-CHLORO-N,N,5-TRIMETHYL-4-OXO-3-PHENYL-3,5-DIHYDRO-4H-PYRIDAZINO[4,5-B]INDOLE-1-ACETAMIDE AS A BIOMARKER OF PERIPHERAL BENZODIAZEPINE RECEPTOR LEVELS | SANOFI-AVENTIS (FR) | 2010-05-06 | — | — | WO | disclosed |
| EP-2012833-A2 | RADIOLABELED DIHYDROTETRABENAZINE DERIVATIVES AND THEIR USE AS IMAGING AGENTS | The Trustees Of The University Of Pennsylvania (US) | 2009-01-14 | — | — | EP | disclosed |
| US-20080050312-A1 | Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-02-28 | — | — | US | disclosed |
| WO-2007130365-A2 | RADIOLABELED DIHYDROTETRABENAZINE DERIVATIVES AND THEIR USE AS IMAGING AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20060120956-A1 | Imaging agents comprising barbituric acid derivatives | KOPKA KLAUS | 2006-06-08 | — | — | US | disclosed |
| EP-1549317-A1 | IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES | GE Healthcare Limited (GB) | 2005-07-06 | — | — | EP | disclosed |
| US-20040097522-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-05-20 | — | — | US | disclosed |
| WO-2004032936-A1 | IMPROVED IMAGING AGENTS COMPRISING BARBITURIC ACID DERIVATIVES | AMERSHAM PLC (GB) | 2004-04-22 | — | — | WO | disclosed |
| EP-1349859-A2 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002050077-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11071794-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | SLC18A2, SLC6A3, SLC6A2 | TAAR1 208/4885GAA 492/4885HSD17B10 616/4885 |
| US-12544463-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | SLC18A2, SLC6A3, SLCO1B3 | TAAR1 220/4885GAA 2784/4885HSD17B10 1530/4885 |
| US-20210346526-A1 | NOVEL DEUTERIUM SUBSTITUTED POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS AND THEIR PHARMACOLOGICAL APPLICATION | SLC18A2, SLC6A3, SLC6A2 | TAAR1 181/4885GAA 469/4885HSD17B10 631/4885 |
| US-10912849-B2 | Deuterium substituted positron emission tomography (PET) imaging agents and their pharmacological application | SLC18A2, SLC6A3, SLC6A2 | TAAR1 208/4885GAA 492/4885HSD17B10 616/4885 |
| US-20060120956-A1 | Imaging agents comprising barbituric acid derivatives | CA5A, GABRA5, CA5B | TAAR1 673/4885GAA 2029/4885HSD17B10 2709/4885 |
| US-20080050312-A1 | Radiolabeled dihydrotetrabenazine derivatives and their use as imaging agents | SLC18A2, SLC18A3, SLC6A2 | TAAR1 133/4885GAA 140/4885HSD17B10 471/4885 |
| US-20040097522-A1 | Triazolopyrimidines | Q6ZSR9, CYP4X1, DDT | TAAR1 6/4885GAA 2506/4885HSD17B10 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.