Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395621 | 0.84 | KMT2A (0.41) | ACHERAPGEF4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24248250 | 0.84 | ALDH1A1 (0.49) | ACHEOPRM1RAPGEF4TSHRALDH1A1 | |
| SCHEMBL24237839 | 0.83 | CXCR2 (0.51) | ACHEOPRM1RAPGEF4TSHRALDH1A1 | |
| SCHEMBL9228264 | 0.81 | ACHE (0.50) | ACHEOPRM1TSHRALDH1A1TP53 | |
| SCHEMBL11405224 | 0.79 | ACHE (0.48) | ACHEOPRM1TSHRALDH1A1TP53 | |
| SCHEMBL31370923 | 0.79 | ACHE (0.48) | ACHEOPRM1TSHRALDH1A1TP53 | |
| SCHEMBL21876495 | 0.79 | ACHE (0.48) | ACHEOPRM1TSHRALDH1A1TP53 | |
| SCHEMBL2927525 | 0.79 | ALDH1A1 (0.54) | ACHERAPGEF4TSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1809448 | 0.77 | ACHE (0.46) | ACHEOPRM1TSHRALDH1A1TP53 | |
| SCHEMBL11660041 | 0.77 | TRPA1 (0.43) | ACHEOPRM1TSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20220037591-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | ACHE 3958/4885OPRM1 570/4885RAPGEF4 4795/4885 |
| US-20220037591-A1 | Polycyclic aromatic compound | F11, C1R, RNF31 | ACHE 3958/4885OPRM1 570/4885RAPGEF4 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.