Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24237483 | 0.80 | MAPT (0.44) | ALKBH5FTOCYP1A2CYP2A6TSHR | |
| SCHEMBL24237500 | 0.77 | CYP1A2 (0.40) | ALKBH5FTOCYP1A2CYP2A6TSHR | |
| SCHEMBL21793464 | 0.76 | ALKBH5 (0.58) | ALKBH5FTOCYP1A2CYP2A6TSHR | |
| SCHEMBL22336514 | 0.71 | CDC25A (0.44) | ALKBH5FTOCYP1A2CYP2A6TSHR | |
| SCHEMBL13564048 | 0.66 | ALKBH5 (0.67) | ALKBH5FTOCYP1A2CYP2A6TSHR | |
| SCHEMBL4071459 | 0.66 | TRPA1 (0.55) | CYP1A2CYP2A6TSHRHTR1BMAPT | |
| Dimethylamine SCHEMBL6102519 | 0.66 | TRPA1 (0.55) | CYP1A2CYP2A6TSHRHTR1BMAPT | |
| SCHEMBL40704 | 0.66 | — | — | |
| SCHEMBL5494561 | 0.66 | TRPA1 (0.61) | CYP1A2CYP2A6TSHRHTR1BMAPT | |
| SCHEMBL21793466 | 0.65 | ALKBH5 (0.39) | ALKBH5FTOCYP1A2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20220037591-A1 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11877506-B2 | Polycyclic aromatic compound | F11, C1R, RNF31 | ALKBH5 3438/4885FTO 4137/4885CYP1A2 133/4885 |
| US-20220037591-A1 | Polycyclic aromatic compound | F11, C1R, RNF31 | ALKBH5 3438/4885FTO 4137/4885CYP1A2 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.