Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12448116 | 0.87 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA4ALDH1A1HTT | |
| SCHEMBL22305723 | 0.82 | LMNA (0.38) | CHRNB2CHRNB4CHRNA4ALDH1A1HRH3 | |
| SCHEMBL25089676 | 0.81 | KDM4C (0.36) | CHRNB2CHRNB4CHRNA4ALDH1A1HTT | |
| SCHEMBL329452 | 0.78 | ARG1 (0.35) | ALDH1A1HRH3KDM4EARG1ARG2 | |
| SCHEMBL25089677 | 0.76 | KDM4C (0.38) | CHRNB2CHRNB4CHRNA4ALDH1A1HTT | |
| SCHEMBL4393706 | 0.76 | SLC6A2 (0.39) | ALDH1A1KDM4EARG1ARG2TDP1 | |
| SCHEMBL5255471 | 0.76 | LMNA (0.46) | ALDH1A1LMNATDP1 | |
| SCHEMBL408247 | 0.76 | ALDH1A1 (0.56) | CHRNB2CHRNB4CHRNA4ALDH1A1HTT | |
| SCHEMBL10125881 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EARG1ARG2 | |
| SCHEMBL5255466 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HRH3KDM4EARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242323-B2 | Inhibition of OLIG2 activity | Curtana Pharmaceuticals, Inc. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242323-B2 | Inhibition of OLIG2 activity | POU2F2, ING2, PAX2 | CHRNB2 762/4885CHRNB4 2079/4885CHRNA4 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.