Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18461006 | 0.79 | IDO1 (0.33) | ALDH1A1MAPTMETAP2CYP1A2CYP2A6 | |
| SCHEMBL24246238 | 0.78 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28645887 | 0.77 | IDO1 (0.32) | ALDH1A1MAPTMETAP2CYP1A2CYP2A6 | |
| Iodide SCHEMBL28621234 | 0.77 | IDO1 (0.32) | ALDH1A1MAPTMETAP2CYP1A2CYP2A6 | |
| SCHEMBL1335872 | 0.76 | KMT2A (0.44) | ALDH1A1MAPTMETAP2CYP1A2CYP2A6 | |
| Dimethylamine SCHEMBL27480944 | 0.74 | CYP1A2 (0.39) | ALDH1A1MAPTCYP1A2CYP2A6TSHR | |
| SCHEMBL3700950 | 0.72 | POLB (0.33) | ALDH1A1MAPTMETAP2CYP1A2CYP2A6 | |
| SCHEMBL37955 | 0.71 | TSHR (0.45) | ALDH1A1MAPTCYP1A2CYP2A6TSHR | |
| SCHEMBL29352563 | 0.71 | TSHR (0.45) | ALDH1A1MAPTCYP1A2CYP2A6TSHR | |
| SCHEMBL5494672 | 0.71 | TSHR (0.45) | ALDH1A1MAPTCYP1A2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3086815-B1 | SULFONAMIDE-CONTAINING LINKAGE SYSTEMS FOR DRUG CONJUGATES | ZYMEWORKS INC (CA) | 2022-02-09 | — | — | EP | disclosed |