Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808938 | 0.82 | PSMB1 (0.48) | ITGB3ITGA2BKDM4EKMT2ANLRP3 | |
| SCHEMBL20808748 | 0.82 | LMNA (0.46) | ITGB3ITGA2BKDM4EKMT2ANLRP3 | |
| SCHEMBL21025554 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2BKDM4EKMT2ANLRP3 | |
| SCHEMBL1687421 | 0.78 | KDM4E (0.57) | KDM4EKMT2ANLRP3ALDH1A1POLB | |
| SCHEMBL20786908 | 0.69 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EKMT2ANLRP3 | |
| SCHEMBL31306252 | 0.69 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EKMT2ANLRP3 | |
| SCHEMBL1590065 | 0.67 | PARP1 (0.65) | KDM4EALDH1A1LMNAL3MBTL1CYP3A4 | |
| SCHEMBL19145535 | 0.66 | KMT2A (0.60) | ITGB3ITGA2BKMT2A | |
| SCHEMBL20808986 | 0.66 | LMNA (0.44) | ITGB3ITGA2BKDM4EKMT2ALMNA | |
| SCHEMBL20808984 | 0.66 | LMNA (0.52) | KDM4EKMT2ANLRP3ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453707-B1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2022-02-16 | — | — | EP | disclosed |