SCHEMBL24250157

SCHEMBL24250157

C=Cc1c(CC)oc2cc(-c3ccccc3)ccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.37
PTPN2 P17706 1/20 0.37
ACP1 P24666 2/20 0.36
PRKDC P78527 1/20 0.36
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC22A12 Q96S37 1/20 0.33
HSD11B1 P28845 1/20 0.33
CYP2C19 P33261 1/20 0.33
PGR P06401 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
MAPKAPK2 P49137 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24884759 0.86 ACP1 (0.36) PTPN1PTPN2ACP1PRKDCMMP12
SCHEMBL24884819 0.82 ALDH1A1 (0.40) PTPN1PTPN2PRKDCMMP12MMP13
SCHEMBL24884725 0.80 ERAP1 (0.41) PTPN1PTPN2ACP1PRKDCGAA
SCHEMBL20352558 0.79 EYA3 (0.45) PTPN1SLC22A12CYP2C19PGRPTGS1
SCHEMBL24884712 0.75 ALDH1A1 (0.38) PTPN1PTPN2PRKDCMMP12MMP13
SCHEMBL26420870 0.72 MMP12 (0.47) PTPN1ACP1PRKDCMMP12MMP13
SCHEMBL18080844 0.72 PRKDC (0.36) PRKDCCYP2C19PTGS1PTGS2KDM4E
SCHEMBL23505229 0.71 HSD11B1 (0.35) PTPN1PTPN2PRKDCMMP12MMP13
SCHEMBL10110901 0.71 PRKDC (0.47) PTPN1PTPN2PRKDCMMP12MMP13
SCHEMBL24884726 0.71 ALDH1A1 (0.41) PTPN1PTPN2ACP1PRKDCMMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052278-A1 DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052278-A1 DISPLAY APPARATUS OCIAD1, OCIAD2, COG4 PTPN1 3910/4885PTPN2 3917/4885ACP1 3718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.