SCHEMBL24251348

SCHEMBL24251348

c1ccc(-c2ccccc2N(c2ccccc2-c2ccccc2)c2ccc3ccc4c(N(c5ccccc5-c5ccccc5)c5ccccc5-c5ccccc5)ccc5ccc2c3c54)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.33
CDK4 P11802 5/20 0.33
CCND1 P24385 5/20 0.33
HSD17B10 Q99714 4/20 0.33
HPGD P15428 3/20 0.33
CYP1A2 P05177 3/20 0.33
THRB P10828 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
MAPK1 P28482 2/20 0.32
BCL2L1 Q07817 1/20 0.32
CYP2A6 P11509 1/20 0.32
TNF P01375 1/20 0.32
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10354005 0.92 CDK4 (0.31) ALDH1A1CDK4CCND1HSD17B10HPGD
SCHEMBL18810731 0.91 HSD17B1 (0.36) CDK4CCND1THRBATML3MBTL1
SCHEMBL18776726 0.89 PDCD1 (0.37) ALDH1A1CDK4CCND1HSD17B10HPGD
SCHEMBL16639341 0.89 CASP3 (0.30) CDK4CCND1CASP3SENP8SENP7
SCHEMBL29636227 0.89 CASP3 (0.30) CDK4CCND1CASP3SENP8SENP7
SCHEMBL15461336 0.89 CASP3 (0.30) CDK4CCND1CASP3SENP8SENP7
SCHEMBL15463078 0.87 ALDH1A1 (0.39) ALDH1A1HSD17B10CYP1A2TSHRATM
SCHEMBL25027776 0.87 ALDH1A1 (0.37) ALDH1A1CDK4CCND1HSD17B10HPGD
SCHEMBL15461353 0.86 NCOA1 (0.39) ALDH1A1HPGD
SCHEMBL15461356 0.86 CDK4 (0.33) CDK4CCND1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220052263-A1 AMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220052263-A1 AMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC2, ODC1, AOC1 ALDH1A1 15/4885CDK4 2021/4885CCND1 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.