Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2B | P41595 | 4/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23894376 | 0.75 | HTR2A (0.38) | HTR2AHTR2CHTR2BTNFRIPK1 | |
| SCHEMBL16638710 | 0.75 | KMT2A (0.36) | SLC6A2SLC6A4 | |
| SCHEMBL78627 | 0.70 | TNF (0.34) | HTR2AHTR2CHTR2BTNFRIPK1 | |
| SCHEMBL10212099 | 0.68 | ACHE (0.44) | HTR2AHTR2BSLC6A2SLC6A4CYP2D6 | |
| SCHEMBL24252062 | 0.68 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12680312 | 0.68 | CA1 (0.31) | — | |
| SCHEMBL17294834 | 0.67 | ABCB11 (0.45) | — | |
| SCHEMBL6764184 | 0.67 | SOS1 (0.44) | HTR2ASLC6A4 | |
| SCHEMBL24252041 | 0.67 | HTR2C (0.34) | HTR2AHTR2CHTR2BRIPK1 | |
| SCHEMBL9847889 | 0.66 | TNF (0.46) | HTR2AHTR2CHTR2BTNFRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048915-A1 | Nitrogen-containing Heterocyclic Compound and Composition Thereof, Preparation Method Therefor, and Application Thereof | MAPK11, WEE1, NOS1 | HTR2A 4415/4885HTR2C 3134/4885HTR2B 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.