SCHEMBL24254797

SCHEMBL24254797

Fc1c(F)c(F)c(-c2c(F)c(F)c(N(c3cccc(-c4ccc(-c5ccccc5)cc4)c3)c3c(F)c(F)c(-c4c(F)c(F)c(F)c(F)c4F)c(F)c3F)c(F)c2F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.34
ACMSD Q8TDX5 2/20 0.33
TAAR1 Q96RJ0 2/20 0.33
HDAC8 Q9BY41 2/20 0.33
MAOA P21397 1/20 0.33
ESR2 Q92731 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
ACLY P53396 1/20 0.33
ALOX5 P09917 1/20 0.32
CETP P11597 2/20 0.32
DHFR P00374 1/20 0.32
HNF4A P41235 1/20 0.32
MCL1 Q07820 1/20 0.32
NPC1 O15118 1/20 0.32
PTPN1 P18031 1/20 0.31
HSD17B1 P14061 2/20 0.31
HSD17B2 P37059 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24254796 0.87 RPS6KA3 (0.31) HNF4A
SCHEMBL24254698 0.86 AKR1C2 (0.34)
SCHEMBL24254694 0.86 ALDH1A1 (0.35) MGLLTAAR1
SCHEMBL24254807 0.82 ALDH1A1 (0.38)
SCHEMBL24254702 0.78 SYK (0.32)
SCHEMBL23079499 0.76 MGLL (0.45) MGLLACMSDTAAR1MAOAESR2
SCHEMBL20100709 0.76 ALDH1A1 (0.39) MGLL
SCHEMBL10029829 0.75 MGLL (0.48) MGLLACMSDHDAC8MAOAHDAC4
SCHEMBL18680557 0.75 MGLL (0.48) MGLLACMSDHDAC8MAOAHDAC4
SCHEMBL24309151 0.74 ALDH1A1 (0.48) MGLLACMSDTAAR1MAOAESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022034907-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2022-02-17 WO disclosed