Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528206 | 0.82 | PNP (0.54) | LMNA | |
| SCHEMBL20908767 | 0.82 | ALDH1A1 (0.59) | HPGDALDH1A1LMNAALBMAPK1 | |
| SCHEMBL4858272 | 0.82 | HPGD (0.59) | HPGDLMNANT5EPAX8 | |
| SCHEMBL22577530 | 0.79 | HPGD (0.48) | SLC29A1HPGDLMNANT5EPAX8 | |
| SCHEMBL20547890 | 0.79 | ADORA2A (0.55) | SLC29A1HPGDLMNANT5EPAX8 | |
| SCHEMBL646777 | 0.77 | CYP1A2 (0.46) | SLC29A1LMNANT5ECYP1A2 | |
| SCHEMBL20547587 | 0.77 | MEN1 (0.48) | HPGDLMNAPAX8 | |
| SCHEMBL4370984 | 0.76 | CYP1A2 (0.45) | SLC29A1LMNANT5ECYP1A2 | |
| SCHEMBL6858256 | 0.76 | CYP1A2 (0.45) | SLC29A1LMNANT5ECYP1A2 | |
| SCHEMBL24258664 | 0.76 | LMNA (0.42) | ALDH1A1LMNANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |