Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258540 | 0.84 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL24258539 | 0.82 | SLC29A1 (0.42) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL4528206 | 0.82 | PNP (0.54) | LMNAPNPTP53HTTPDE4D | |
| SCHEMBL24258568 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL4858272 | 0.77 | HPGD (0.59) | LMNATP53HPGD | |
| SCHEMBL19325462 | 0.76 | CYP1A2 (0.67) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL4409629 | 0.75 | CYP1A2 (0.66) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL22577530 | 0.75 | HPGD (0.48) | LMNATP53PDE4DPDE3AHPGD | |
| SCHEMBL20547890 | 0.75 | ADORA2A (0.55) | LMNATP53PDE4DPDE3AHPGD | |
| SCHEMBL21362298 | 0.74 | ALDH1A1 (0.64) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |