Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HINT1 | P49773 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15629331 | 0.85 | TAS1R3 (0.44) | TAS1R3TAS1R1P2RX3P2RX2BCHE | |
| SCHEMBL24258545 | 0.82 | TAS1R3 (0.51) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL15629394 | 0.76 | PDE4A (0.41) | BCHEADORA3SLC29A1NT5E | |
| SCHEMBL15629304 | 0.73 | ADORA3 (0.46) | ADORA3SLC29A1 | |
| SCHEMBL15629262 | 0.73 | ADORA3 (0.47) | P2RX3ADORA3 | |
| SCHEMBL15629335 | 0.73 | THRB (0.39) | NT5E | |
| SCHEMBL20908479 | 0.70 | TAS1R3 (0.48) | TAS1R3TAS1R1P2RX3P2RX2SLC29A1 | |
| SCHEMBL25691245 | 0.68 | P2RX3 (0.58) | TAS1R3TAS1R1P2RX3P2RX2 | |
| SCHEMBL24059908 | 0.68 | ADORA3 (0.55) | TAS1R3TAS1R1P2RX3P2RX2ADORA3 | |
| SCHEMBL21423035 | 0.68 | HIF1A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487553-B2 | Boranophosphate analogues of cyclic nucleotides | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2016-11-08 | — | — | US | disclosed |
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2014-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088033-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | NT5C2, NT5E, ENPP3 | TAS1R3 3734/4885TAS1R1 4075/4885P2RX3 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.