Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 10/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.44 |
| ▸ | FHIT | P49789 | 4/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 5/20 | 0.43 |
| ▸ | NADK | O95544 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258562 | 0.89 | BCHE (0.42) | IMPDH2ADH1AFHITIMPDH1NADK | |
| SCHEMBL24444131 | 0.82 | ADH1A (0.43) | IMPDH2ADH1AIMPDH1NADK | |
| SCHEMBL21264014 | 0.80 | IMPDH2 (0.54) | IMPDH2NT5EADH1AFHITIMPDH1 | |
| SCHEMBL21263869 | 0.79 | AHCY (0.43) | IMPDH2ADH1AFHITIMPDH1NADK | |
| SCHEMBL24444141 | 0.79 | IMPDH2 (0.46) | IMPDH2NT5EADH1AFHITIMPDH1 | |
| SCHEMBL21263989 | 0.78 | NT5E (0.54) | IMPDH2NT5E | |
| SCHEMBL21263919 | 0.76 | FHIT (0.41) | IMPDH2ADH1AFHITIMPDH1NADK | |
| SCHEMBL29332501 | 0.76 | NT5E (0.65) | NT5E | |
| SCHEMBL24722228 | 0.74 | NT5E (0.57) | NT5EFHIT | |
| SCHEMBL21362281 | 0.73 | NT5E (0.55) | NT5EFHIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752516-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-02-23 | — | — | EP | disclosed |