Sugi Predict

Sugi Predict / Compounds / SCHEMBL2425935

SCHEMBL2425935

SCHEMBL2425935

O=C(CCl)OCCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.63
▸ HCAR2 Q8TDS4 1/20 0.54
▸ APP P05067 1/20 0.54
▸ ESR1 P03372 1/20 0.53
▸ ESR2 Q92731 1/20 0.53
▸ NPC1 O15118 3/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ ALDH1A1 P00352 3/20 0.51
▸ L3MBTL1 Q9Y468 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ AKR1B10 O60218 2/20 0.51
▸ AKR1B1 P15121 2/20 0.51
▸ TP53 P04637 1/20 0.51
▸ GLA P06280 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HIF1A Q16665 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2431281 0.89 LMNA (0.64) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL18076001 0.87 TDP1 (0.58) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL18076009 0.86 TDP1 (0.56) TDP1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL27860099 0.85 TDP1 (0.70) TDP1HCAR2APPESR1ESR2
SCHEMBL22832718 0.84 TDP1 (0.81) TDP1HCAR2APPESR1ESR2
SCHEMBL451184 0.84 TDP1 (0.68) TDP1HCAR2APPESR1ESR2
SCHEMBL9367557 0.82 TDP1 (0.92) TDP1HCAR2APPESR1ESR2
SCHEMBL8890081 0.82 TDP1 (0.66) TDP1HCAR2APPESR1ESR2
SCHEMBL6025448 0.82 TDP1 (0.66) TDP1HCAR2APPESR1ESR2
SCHEMBL245747 0.82 ALDH1A1 (0.66) TDP1HCAR2APPESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773215-B Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-09-02 — — CN claimed
CN-114773215-A Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-07-22 — — CN claimed
CN-102260362-B Atactic multiblock styrene polymer and preparation method thereof UNIV BEIJING CHEMICAL 2013-04-10 — — CN claimed
CN-102260362-A Atactic multiblock styrene polymer and preparation method thereof — 2011-11-30 — — CN claimed
CN-116023544-B Catalyst component for olefin polymerization, preparation method thereof, catalyst and olefin polymerization method 中国石油化工股份有限公司 2024-12-06 — — CN disclosed
CN-116023542-B Catalyst component, catalyst and preparation method and application thereof 中国石油化工股份有限公司 2024-09-17 — — CN disclosed
CN-114773215-B Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-09-02 — — CN disclosed
CN-114773215-A Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-07-22 — — CN disclosed
CN-102260362-B Atactic multiblock styrene polymer and preparation method thereof UNIV BEIJING CHEMICAL 2013-04-10 — — CN disclosed
US-20130046087-A1 Substituted Cyclodextrin Derivatives Useful As Intermediates For Producing Biologically Active Materials ARCARIOS BV (NL) 2013-02-21 — — US disclosed
EP-2550299-A2 Substituted cyclodextrin derivatives and process for their preparation Arcarios B.V. (NL) 2013-01-30 — — EP disclosed
CN-102834416-A Substituted cyclodextrin derivatives useful as intermediates for producing biologically active materials ARCARIOS BV 2012-12-19 — — CN disclosed
US-20030083513-A1 Functional alcohol releasing substance KAO CORPORATION (JP) 2003-05-01 — — US disclosed
US-6486333-B1 Functional alcohol releasing substance KAO CORPORATION (JP) 2002-11-26 — — US disclosed
EP-1099689-A2 Functional alcohol releasing substance Kao Corporation (JP) 2001-05-16 — — EP disclosed
CN-1192776-A Betaine esters capable of liberating alcohols PROCTER & GAMBLE (US) 1998-09-09 — — CN disclosed
EP-0752465-A1 Betaine esters for delivery of alcohols THE PROCTER & GAMBLE COMPANY (US) 1997-01-08 — — EP disclosed
WO-1996038528-A1 BETAINE ESTERS FOR DELIVERY OF ALCOHOLS THE PROCTER & GAMBLE COMPANY (US) 1996-12-05 — — WO disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 — — US disclosed
US-3970678-A Organotin mercaptide process CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083513-A1 Functional alcohol releasing substance TACR2, ADH1A, ADH5 TDP1 4065/4885HCAR2 201/4885APP 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.