SCHEMBL451184

SCHEMBL451184

O=C(CC(=O)OCCc1ccccc1)OCCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.68
HCAR2 Q8TDS4 1/20 0.58
APP P05067 1/20 0.57
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALDH1A1 P00352 2/20 0.54
AKR1B10 O60218 2/20 0.54
AKR1B1 P15121 2/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13560198 0.93 TDP1 (0.59) TDP1HCAR2APPESR1ESR2
SCHEMBL451185 0.92 TDP1 (0.63) TDP1HCAR2APPESR1ESR2
SCHEMBL27843168 0.91 TDP1 (0.58) TDP1HCAR2APPSMN1; SMN2AKR1B10
SCHEMBL8881369 0.89 TDP1 (0.59) TDP1HCAR2APPESR1ESR2
SCHEMBL3345622 0.89 TDP1 (0.59) TDP1HCAR2APPESR1ESR2
SCHEMBL7290583 0.88 TDP1 (0.75) TDP1HCAR2APPESR1ESR2
SCHEMBL8465673 0.88 LMNA (0.68) TDP1NPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL22832718 0.88 TDP1 (0.81) TDP1HCAR2APPESR1ESR2
SCHEMBL10438785 0.87 TDP1 (0.53) TDP1HCAR2APPESR1ESR2
SCHEMBL245747 0.86 ALDH1A1 (0.66) TDP1HCAR2APPESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104558290-A Components of catalyst for polymerization of olefins and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558291-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558292-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558293-A Catalyst component for olefin polymerization and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
US-20260117617-A1 EXPANDABLE POLYMER GROUT FOR SAND CONTROL IN A WELL CHEVRON USA INC (US) 2026-04-30 US disclosed
US-12612839-B1 Expandable polymer grout for sand control in a well CHEVRON U.S.A. INC. (US) 2026-04-28 US disclosed
EP-3898205-B1 SURFACE TREATMENT TO ENHANCE BONDING OF COMPOSITE MATERIALS CYTEC IND INC (US) 2026-03-11 EP disclosed
US-20260063011-A1 EXPANDABLE POLYMER GROUT FOR WELLBORE APPLICATIONS CHEVRON USA INC (US) 2026-03-05 US disclosed
US-12552959-B2 Aqueous coating composition for corrosion protection ALLNEX AUSTRIA GMBH (AT) 2026-02-17 US disclosed
US-12428931-B2 Cement top jobs in wellbore annuli using expandable compositions CHEVRON U.S.A. INC. (US) 2025-09-30 US disclosed
EP-4131548-B1 NON-AQUEOUS ELECTROLYTE FOR BATTERY, PRECURSOR FOR LITHIUM SECONDARY BATTERY, METHOD FOR MANUFACTURING LITHIUM SECONDARY BATTERY, LITHIUM SECONDARY BATTERY, PHOSPHAZENE COMPOUND, AND ADDITIVE FOR BATTERY MITSUI CHEMICALS INC (JP) 2025-08-27 EP disclosed
US-20250250878-A1 EXPANDABLE POLYMER GROUT FOR SEALING SUBTERRANEAN FORMATIONS CHEVRON U.S.A. INC. 2025-08-07 US disclosed
US-5849855-A Blocked polyisocyanate composition and one-pack thermocuring resin composition comprising the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1998-12-15 US disclosed
WO-1998047906-A1 PHOSPHONIC ACID DERIVATIVES GUILFORD PHARMACEUTICALS INC. (US) 1998-10-29 WO disclosed
EP-0865421-A1 ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS GLAXO GROUP LIMITED (GB) 1998-09-23 EP disclosed
WO-1997021665-A1 ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS GLAXO GROUP LIMITED (GB) 1997-06-19 WO disclosed
EP-0361365-A1 Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use E.R. SQUIBB & SONS, INC. (US) 1990-04-04 EP disclosed
EP-0040418-B1 PROCESS FOR PREPARING AN 1H-INDAZOL-3-YLACETIC ACID DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-07-03 EP disclosed
EP-0040418-A1 Process for preparing an 1H-indazol-3-ylacetic acid derivative FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-11-25 EP disclosed
EP-0008759-A2 New process for preparing an 1H-indazol-3-ylacetic acid derivative FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552959-B2 Aqueous coating composition for corrosion protection ADH1A, ADH1C, TET1 TDP1 1179/4885HCAR2 2108/4885APP 3302/4885
US-20260063011-A1 EXPANDABLE POLYMER GROUT FOR WELLBORE APPLICATIONS HPSE, HIRIP3, WEE2 TDP1 4342/4885HCAR2 452/4885APP 3631/4885
US-12612839-B1 Expandable polymer grout for sand control in a well GET3, USE1, WEE2 TDP1 3906/4885HCAR2 2327/4885APP 1652/4885
US-20260117617-A1 EXPANDABLE POLYMER GROUT FOR SAND CONTROL IN A WELL GET3, WEE1, WEE2 TDP1 4024/4885HCAR2 2688/4885APP 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.