Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359574 | 0.75 | RXRA (0.49) | RARBRARGRXRARXRBRXRG | |
| SCHEMBL24806898 | 0.69 | BACE1 (0.34) | PGR | |
| SCHEMBL27259756 | 0.67 | AKR1B1 (0.43) | — | |
| SCHEMBL9721391 | 0.63 | OPRM1 (0.41) | RARBRARGRXRARXRBRXRG | |
| SCHEMBL169731 | 0.60 | OPRM1 (0.39) | — | |
| SCHEMBL29401440 | 0.60 | OPRM1 (0.39) | — | |
| SCHEMBL3179509 | 0.60 | CYP3A4 (0.37) | RARBRARGRXRARXRBRXRG | |
| SCHEMBL27259563 | 0.59 | RARA (0.51) | RARBRARGRXRA | |
| SCHEMBL19259616 | 0.59 | RARA (0.37) | RARBRARGRXRA | |
| SCHEMBL2353102 | 0.59 | HTR2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044216-B1 | NOVEL AND SPECIFIC INHIBITORS OF CYTOCHROME P450 26 RETINOIC ACID HYDROXYLASE | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2022-02-23 | — | — | EP | disclosed |