Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612256 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP9FKBP1AADRB2 | |
| SCHEMBL24260228 | 0.79 | XPNPEP1 (0.40) | DPP4DPP8DPP9FKBP1AADRB2 | |
| SCHEMBL5556194 | 0.78 | DPP4 (0.46) | DPP4DPP8DPP9ALDH1A1HRH3 | |
| SCHEMBL18792776 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9ALDH1A1HRH3 | |
| SCHEMBL20812666 | 0.77 | OPRD1 (0.49) | DPP4DPP8DPP9ALDH1A1KDM1A | |
| SCHEMBL19480240 | 0.75 | POLB (0.44) | DPP4DPP8ALDH1A1POLBL3MBTL1 | |
| SCHEMBL17886532 | 0.71 | CYP1A2 (0.47) | ALDH1A1 | |
| SCHEMBL10245382 | 0.71 | CYP1A2 (0.47) | ALDH1A1 | |
| SCHEMBL18532187 | 0.69 | RAB9A (0.41) | DPP4DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL20812496 | 0.68 | KDM1A (0.45) | ALDH1A1KDM1ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPA1, TRPV2 | DPP4 746/4885DPP8 1238/4885DPP9 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.