SCHEMBL24260259

SCHEMBL24260259

CC(C)C(=O)Oc1ccccc1NC1CCN(C)CC1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 10/20 0.46
▸ SSTR1 P30872 7/20 0.46
▸ KDM4E B2RXH2 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ DRD2 P14416 1/20 0.42
▸ CHRM3 P20309 1/20 0.42
▸ ADRB2 P07550 1/20 0.41
▸ ADRB1 P08588 1/20 0.41
▸ ADRB3 P13945 1/20 0.41
▸ CDK1 P06493 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24260224 0.89 ELANE (0.45) DRD2ADRB2MEN1KMT2ADRD3
SCHEMBL24260258 0.85 KDM4E (0.49) SSTR4SSTR1KDM4ETDP1DRD2
SCHEMBL24260561 0.83 KAT2B (0.44) MEN1KMT2A
SCHEMBL24260504 0.81 SSTR4 (0.50) SSTR4SSTR1
SCHEMBL24260213 0.75 CYP3A4 (0.44) SSTR4SSTR1CHRM3KMT2ACYP3A4
SCHEMBL24260231 0.73 PTGS2 (0.46) KDM4ETDP1MEN1KMT2A
SCHEMBL12415575 0.73 KDM4E (0.55) KDM4EKMT2A
SCHEMBL24260613 0.73 ELANE (0.47) KDM4EDRD2ADRB2MEN1KMT2A
SCHEMBL24260426 0.72 ELANE (0.42) TDP1DRD2MEN1KMT2ADRD3
SCHEMBL22605778 0.72 ALDH1A1 (0.45) KDM4ETDP1CHRM3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820727-B1 Capsaicinoid prodrug compounds and their use in treating medical conditions CENTREXION THERAPEUTICS CORPORATION (US) 2023-11-21 — — US disclosed
US-11820727-B1 Capsaicinoid prodrug compounds and their use in treating medical conditions CENTREXION THERAPEUTICS CORPORATION (US) 2023-11-21 — — US disclosed
US-11254659-B1 Capsaicinoid prodrug compounds and their use in treating medical conditions CENTREXION THERAPEUTICS CORPORATION (US) 2022-02-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820727-B1 Capsaicinoid prodrug compounds and their use in treating medical conditions TRPV1, TRPV2, TRPV3 SSTR4 1067/4885SSTR1 1810/4885KDM4E 3063/4885
US-11254659-B1 Capsaicinoid prodrug compounds and their use in treating medical conditions TRPV1, TRPA1, TRPV2 SSTR4 1474/4885SSTR1 1480/4885KDM4E 3279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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