Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.44 |
| ▸ | CLK1 | P49759 | 2/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4903332 | 0.83 | LIMK1 (0.50) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL24623700 | 0.81 | LIMK1 (0.37) | LIMK1CLK1CDC7DBF4NPC1 | |
| SCHEMBL26423730 | 0.77 | LIMK1 (0.36) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL26423739 | 0.77 | LIMK1 (0.36) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL29717311 | 0.77 | GPR3 (0.48) | LIMK1L3MBTL1KDM4EMAPTHPGD | |
| SCHEMBL3038100 | 0.77 | GPR3 (0.48) | LIMK1L3MBTL1KDM4EMAPTHPGD | |
| SCHEMBL24270401 | 0.77 | LIMK1 (0.41) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL2855389 | 0.77 | CLK1 (0.51) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL11884989 | 0.76 | LIMK1 (0.39) | LIMK1CLK1CDC7DBF4IKBKB | |
| SCHEMBL24624013 | 0.74 | CLK1 (0.31) | LIMK1CLK1CDC7DBF4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) | 2022-07-14 | — | — | US | disclosed |
| US-20220069240-A1 | COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | NR0B2, FPR3, NPR3 | LIMK1 3355/4885CLK1 2296/4885CDC7 1709/4885 |
| US-20220069240-A1 | COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | ORC3, LAGE3, ERCC1 | LIMK1 272/4885CLK1 982/4885CDC7 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.