SCHEMBL2428164

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1136382	0.91	MAOB (0.40)	MAOBNPC1RAB9AMAOAIDO1
	SCHEMBL2432282	0.88	NPC1 (0.37)	MAOBNPC1RAB9AMAOAIDO1
	SCHEMBL2433158	0.87	ALDH1A1 (0.39)	MAOBNPC1RAB9AMAOAIDO1
	SCHEMBL2432114	0.83	NPC1 (0.37)	NPC1RAB9AIDO1KDM4EALDH1A1
	SCHEMBL2432159	0.83	NPC1 (0.37)	NPC1RAB9AIDO1KDM4EALDH1A1
	SCHEMBL1136119	0.82	MAOB (0.40)	MAOBNPC1RAB9AMAOAIDO1
	SCHEMBL2429424	0.81	DYRK1A (0.39)	NPC1RAB9APRKAA1KDM4EALDH1A1
	SCHEMBL2432859	0.81	ADORA3 (0.43)	NPC1RAB9AIDO1KDM4EALDH1A1
	SCHEMBL2429944	0.81	MGAM (0.35)	NPC1RAB9AIDO1KDM4EALDH1A1
	SCHEMBL2438266	0.80	PDE3B (0.38)	MAOBNPC1RAB9AMAOAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.